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Structurally related nucleotides as selective agonists and antagonists at P2Y1 receptors.
Jacobson KA, Moro S, Hoffmann C, Kim YC, Kim HS, Ravi RG, Harden TK, Boyer JL. Jacobson KA, et al. Farmaco. 2001 Jan-Feb;56(1-2):71-5. doi: 10.1016/s0014-827x(01)01023-0. Farmaco. 2001. PMID: 11347970 Free PMC article. Review.
The P2Y1 receptor responds to adenine nucleotides and is present in platelets, heart, smooth muscles prostate, ovary, and brain. A selective antagonist may be useful as an antithrombotic agent. ...
The P2Y1 receptor responds to adenine nucleotides and is present in platelets, heart, smooth muscles prostate, ovary, and brain. A se …
Differing leukocyte gene expression profiles associated with fatigue in patients with prostate cancer versus chronic fatigue syndrome.
Light KC, Agarwal N, Iacob E, White AT, Kinney AY, VanHaitsma TA, Aizad H, Hughen RW, Bateman L, Light AR. Light KC, et al. Psychoneuroendocrinology. 2013 Dec;38(12):2983-95. doi: 10.1016/j.psyneuen.2013.08.008. Epub 2013 Sep 6. Psychoneuroendocrinology. 2013. PMID: 24054763 Free PMC article.
BACKGROUND: Androgen deprivation therapy (ADT) often worsens fatigue in patients with prostate cancer, producing symptoms similar to chronic fatigue syndrome (CFS). ...Correlations with fatigue severity implicated DBI for both patient groups and P2RY1 for PCF only. …
BACKGROUND: Androgen deprivation therapy (ADT) often worsens fatigue in patients with prostate cancer, producing symptoms similar to …
Cloning and tissue distribution of the human P2Y1 receptor.
Janssens R, Communi D, Pirotton S, Samson M, Parmentier M, Boeynaems JM. Janssens R, et al. Biochem Biophys Res Commun. 1996 Apr 25;221(3):588-93. doi: 10.1006/bbrc.1996.0640. Biochem Biophys Res Commun. 1996. PMID: 8630005
Northern blot analysis detected a 6.7 kilobase messenger RNA in most human tissues, the strongest signals being observed in prostate and ovary....
Northern blot analysis detected a 6.7 kilobase messenger RNA in most human tissues, the strongest signals being observed in prostate …
ATP modulates noradrenaline release by activation of inhibitory P2Y receptors and facilitatory P2X receptors in the rat vas deferens.
Queiroz G, Talaia C, Gonçalves J. Queiroz G, et al. J Pharmacol Exp Ther. 2003 Nov;307(2):809-15. doi: 10.1124/jpet.103.054809. Epub 2003 Sep 9. J Pharmacol Exp Ther. 2003. PMID: 12966150
The role of ATP on the modulation of noradrenaline release elicited by electrical stimulation (100 pulses/8 Hz) was studied in the prostatic portion of rat vas deferens preincubated with [3H]noradrenaline. ...Under the same conditions, apyrase attenuated, whereas the ecton …
The role of ATP on the modulation of noradrenaline release elicited by electrical stimulation (100 pulses/8 Hz) was studied in the prosta …